The ENIGMA-II trial by Dr. Matthew Vella @mjv.igee #Anaesthesia #anaesthetics #anesthesiology #anesthesia #anesthetic #abcsofanaesthesia #medicine #anesthesiologist #anaesthetist #anesthetist #anaesthesiology #nurse #medical #meded #FOAMed #medicalstudent #ENIGMAtrial # ENIGMA2trial #safety #generalanaesthesia #GA #Nitrousoxide #N2O #Gas #MajorSurgery #cardiacriskfactors Title: The safety of addition of nitrous oxide to general anaesthesia in at-risk patients having major non-cardiac surgery (ENIGMA-II): a […]
Author Archives: Majic Sites
A review of the environmental impacts of desflurane and nitrous oxide By Yannick De Silva What is the problem? Much of the media reports carbon dioxide (CO2) emissions but fails to address the impact that volatile inhaled anaesthetic gases have on the environment. Desflurane, in particular, is thousands of times more potent than CO2 and […]
Definition Hyperkalaemia refers to a state of high serum potassium (K+), typically > 5.5 mmol/L. Potassium is split between intracellular (98%, ~150 mmol/L K+ concentration) and extracellular (2%, ~4-5 mmol/L concentration) compartments. Potassium ions are the main intracellular cation and carry an electrical charge. They establish an electrochemical gradient across the cell membrane known as […]
by Dr. Matthew Vella Title: Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial McCann, M. E., de Graaff, J. C., Dorris, L., Disma, N., Withington, D., Bell, G., Grobler, A., Stargatt, R., Hunt, R. W., Sheppard, S. J., Marmor, J., […]
by Dr. Matthew Vella @mjv.igee #Anaesthesia #anaesthetics #anesthesiology #anesthesia #anesthetic #abcsofanaesthesia #medicine #anesthesiologist #anaesthetist #anesthetist #anaesthesiology #nurse #medical #meded #FOAMed #medicalstudent #geriatrics #trauma #hipfracture #NOF Title: Guideline for the management of hip fractures 2020 Griffiths, R., Babu, S., Dixon, P., Freeman, N., Hurford, D., Kelleher, E., Moppett, I., Ray, D., Sahota, O., Shields, M., & […]
Imagine you arrive at your morning urology list with 7 cystoscopy cases. Your 1st patient is a 60yo male for a rigid cystoscopy. He has a drug eluting stent from an AMI 5 years ago and has functionally declined since. He is 120kg with the usual collection of diabetes, hypertension and hypercholesterolaemia with no previous […]
I remember one stressful case of a patient who was septic, and suffering a post partum haemorrhage. After induction of anesthesia, the patient’s blood pressure dropped precipitously requiring large doses of inotropes. She developed a rash and bronchospasm signifying likely anaphylaxis. How could this unlucky patient have so many complications? We stepped into crisis mode […]
You induce a 60yo male for an aorto-bifemoral bypass with severe leg claudication. He has the expected past history of ischaemic heart disease (STEMI 5 years ago – stents + medical management), diabetes, hypertension, and was a 20-pack year ex-smoker. After a reasonably stable induction, his blood pressure continues to need vasopressor. You administer escalating […]
Definition Hypokalaemia simply means low blood potassium (K+). Mild hypokalaemia refers to a serum potassium concentration of under 3.5mmol/L Severe hypokalaemia indicates less than 2.5mmol/L of potassium in the blood. Potassium is split between intracellular (98%, ~150mmol/L K+ concentration) and extracellular (2%, ~4-5mmol/L concentration) compartments. Potassium ions are the main intracellular cation and carry an […]
Anaesthesia Medical Elective Rotation Welcome to anaesthesia! Your anaesthesia rotation will be one of the most interesting, demanding and hands on rotations during your medical school experience. This document will provide a few insights, expectations, tips and administrative information for your term. Expectations I want to maximise your learning in the time you are […]









